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NICE asthma guidelines: time to re-evaluate the diagnostic value of exercise challenge testing?

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Asthma is a heterogenous chronic inflammatory lower airways disease that affects >350 million of the global population [1]. It is now recognised that securing a diagnosis is often challenging given… Click to show full abstract

Asthma is a heterogenous chronic inflammatory lower airways disease that affects >350 million of the global population [1]. It is now recognised that securing a diagnosis is often challenging given clinical examination can be normal at rest and symptoms have a broad differential diagnosis. In support of this concept, a seminal study by Aaron et al. [2] observed that almost one third of adults with a physician diagnosis showed no clinical or laboratory evidence of asthma when re-examined at 12 months. Similarly, underdiagnosis remains a widespread issue, with estimates ranging between 19% and 73%, depending on the diagnostic methods and population studied [3]. NICE asthma diagnosis recommendations for the use of ECT are based on a limited number of studies that violate current ECT recommendations. Further research is therefore required to re-evaluate the diagnostic value of ECT. https://bit.ly/3iS4smw

Keywords: diagnosis; asthma guidelines; evaluate diagnostic; nice asthma; diagnostic value

Journal Title: ERJ Open Research
Year Published: 2022

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