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Observational study of inhaled corticosteroid treatment for improved expiratory variability index in steroid-naïve asthmatic children

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The Lancet Asthma Commission calls for objective measurements to support asthma diagnosis, especially for children [1]. The expiratory variability index (EVI) is a novel method of testing lung function that… Click to show full abstract

The Lancet Asthma Commission calls for objective measurements to support asthma diagnosis, especially for children [1]. The expiratory variability index (EVI) is a novel method of testing lung function that can be measured passively at night with an impedance pneumography (IP) technique using four skin electrodes and a small body-worn recorder. The aim of EVI is to measure variation in flow–volume curve shapes within 15–45% of the expired volume. It has been demonstrated that normal variations in the curve shapes are mainly caused by comparing different sleep cycles [2], which are reduced in the presence of bronchial obstructions [3]. Inhaled corticosteroid treatment improves expiratory variability index in steroid-naïve asthmatic children aged 4–7 years https://bit.ly/3n4vBT3

Keywords: inhaled corticosteroid; expiratory variability; corticosteroid treatment; variability index

Journal Title: ERJ Open Research
Year Published: 2022

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