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Missing sputum samples are common in asthma intervention studies and successful collection at follow-up is related to improvement in clinical outcomes

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With only modest agreement between airway and systemic eosinophilia, biomarkers directly assessing the level and type of airway inflammation are becoming increasingly important, both for targeting treatment to the individual… Click to show full abstract

With only modest agreement between airway and systemic eosinophilia, biomarkers directly assessing the level and type of airway inflammation are becoming increasingly important, both for targeting treatment to the individual patient and for assessing effect [1]. Several factors significantly impact ability to produce a sputum sample after an anti-inflammatory intervention and these authors argue that the widely used complete-case analysis is inappropriate for paired sputum-based outcome measures https://bit.ly/3qN2pk5

Keywords: sputum samples; intervention; common asthma; asthma intervention; missing sputum; samples common

Journal Title: ERJ Open Research
Year Published: 2022

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