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Dysglycaemia among tuberculosis patients without known diabetes in a low-endemic setting

There is increasing evidence that diabetes mellitus is an important risk factor for tuberculosis (TB) and might affect TB-disease presentation as well as treatment response [1]. The hypothesis is that… Click to show full abstract

There is increasing evidence that diabetes mellitus is an important risk factor for tuberculosis (TB) and might affect TB-disease presentation as well as treatment response [1]. The hypothesis is that an impaired immune response in persons with diabetes mellitus facilitates infection with Mycobacterium tuberculosis and/or progression to TB, and reversely, M. tuberculosis infection may affect glycaemic control [2, 3]. Although the exact causality is unknown, this association between TB and diabetes mellitus is ominous, as the explosive rise in diabetes mellitus worldwide witnessed over the last decades could potentially counteract the positive effect of TB control efforts. With a high prevalence of dysglycaemia (29.1%) among tuberculosis patients without previously known diabetes, this study highlights the importance of comanagement of tuberculosis and diabetes, even in a low-endemic setting https://bit.ly/3Gj0gmN

Keywords: tuberculosis patients; tuberculosis; dysglycaemia among; among tuberculosis; diabetes mellitus; patients without

Journal Title: ERJ Open Research
Year Published: 2022

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