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IKK-mediated CYLD phosphorylation and cellular redox activity

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Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about… Click to show full abstract

Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the pathogenesis require clarification.

Keywords: redox activity; phosphorylation cellular; cellular redox; ikk mediated; cyld phosphorylation; mediated cyld

Journal Title: Molecular Medicine
Year Published: 2022

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