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The pre-amputation pain and the postoperative deafferentation are the risk factors of phantom limb pain: a clinical survey in a sample of Chinese population

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BackgroundTo provide an overview of phantom limb pain (PLP) in China. This includes the prevalence of PLP and possible risk factors.MethodsIn a retrospective study, telephone interviews were conducted with 391… Click to show full abstract

BackgroundTo provide an overview of phantom limb pain (PLP) in China. This includes the prevalence of PLP and possible risk factors.MethodsIn a retrospective study, telephone interviews were conducted with 391 amputation patients who underwent extremity amputations at a tertiary hospital in China.ResultsPLP was found in 29% of the amputees. Pre-amputation pain (OR = 10.4, P = 0.002) and postoperative analgesia (OR = 4.9, P = 0.008) were identified as high-risk factors for PLP. 82.1% of PLP patients experienced pre-amputation pain. The average pain intensity of PLP was 5.1 ± 2.2, with 31.9% having severe intensity. The effects of PLP on the quality of the PLP patients were as follows: 7.8% of the patients had to limit their daily life and 29.0% of the patients had to limit their social activities. 17.3 and 25.7% of patients experienced depression and sleeping disorder respectively, while 18.9% had loss of interest and even 16.1% of PLP patients had attempted suicide. No effective treatments were found in 78.9% of these patients.ConclusionsPLP has markedly affected the lives of patients. Pre-amputation pain and postoperative epidural analgesia might be risk factors for the phantom limb pain after amputation. Prevention of pre-amputation pain and sudden post-amputation deafferentation should be recommended to the amputees.

Keywords: amputation; amputation pain; risk factors; phantom limb; pre amputation; pain

Journal Title: BMC Anesthesiology
Year Published: 2017

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