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Management and short-term outcomes of neonates born to mothers with active perinatal SARS-CoV-2 infection

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Objective We report here on the management and outcomes of neonates born to mothers with active perinatal SARS-CoV-2 infection. Study design In this prospective study, eligible neonates were enrolled in… Click to show full abstract

Objective We report here on the management and outcomes of neonates born to mothers with active perinatal SARS-CoV-2 infection. Study design In this prospective study, eligible neonates were enrolled in a database to track in-hospital outcomes and followed up outpatient periodically till 2 months of age to assess for late onset symptoms of infection. Results From April 2020 to February 2021, 67 mothers with perinatal SARS-CoV-2 infection and 70 at-risk neonates were included. Two neonates (3%) tested positive for SARS-CoV-2 within 48 h of life but remained asymptomatic during hospitalization and at all follow-up periods. Three infants were reported to have a febrile illness in 2 months follow up period, none of which was attributable to SARS-CoV-2. Conclusion Our data supports the emerging evidence which describes a probable low risk of vertical transmission of SARS-CoV-2. We also demonstrate a low risk of post-natal transmission or late-onset symptomatic infection with SARS-CoV-2.

Keywords: outcomes neonates; infection; neonates born; perinatal sars; sars cov; cov infection

Journal Title: BMC Pediatrics
Year Published: 2021

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