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Triglyceride and glucose (TyG) index as a predictor of incident hypertension: a 9-year longitudinal population-based study

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BackgroundHypertension and the triglyceride and glucose index both have been associated with insulin resistance; however, the longitudinal association remains unclear. This study was designed to investigate the longitudinal association between… Click to show full abstract

BackgroundHypertension and the triglyceride and glucose index both have been associated with insulin resistance; however, the longitudinal association remains unclear. This study was designed to investigate the longitudinal association between the triglyceride and glucose index and incident hypertension among the Chinese population.MethodsWe studied 4686 subjects (3177 males and 1509 females) and followed up for 9 years. The subjects were divided into four groups based on the triglyceride and glucose index. Univariate and multivariate Cox regression models were used to analyse the risk factors of hypertension.ResultsAfter 9 years of follow-up, 2047 subjects developed hypertension. The overall 9-year cumulative incidence of hypertension was 43.7%, ranging from 28.5% in quartile 1 to 36.9% in quartile 2, 49.2% in quartile 3 and 59.8% in quartile 4 (p for trend < 0.001). Cox regression analyses indicated that higher triglyceride and glucose index was associated with an increased risk of subsequent incident hypertension.ConclusionThe triglyceride and glucose index can predict the incident hypertension among the Chinese population.

Keywords: index; incident hypertension; triglyceride glucose; glucose index; population

Journal Title: Lipids in Health and Disease
Year Published: 2017

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