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The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity

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The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (R o ), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU).… Click to show full abstract

The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (R o ), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU). We suggest that comparison between the two parameters may assist in better understanding viral transmission dynamics.

Keywords: comparison two; particle plaque; basic reproductive; reproductive number; two parameters; plaque ratio

Journal Title: Virology Journal
Year Published: 2021

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