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Retrospective investigation of IgM antibodies against Zika virus in serum from febrile patients in Mozambique, 2009–2015

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ObjectiveZika virus (ZIKV) has emerged as an important health problem worldwide. The aim of this study was to investigate the occurrence, geographical distribution and trend of immunoglobulin M (IgM) antibodies… Click to show full abstract

ObjectiveZika virus (ZIKV) has emerged as an important health problem worldwide. The aim of this study was to investigate the occurrence, geographical distribution and trend of immunoglobulin M (IgM) antibodies against ZIKV between 2009 and 2015 in Mozambique.ResultsThe median age of participants was 3 years [interquartile range (IQR): 1.0–6.0 years)] and 56.5% (480/850) of them were male. Of the 850 samples, 42 (4.9%) were positive for IgM antibodies against ZIKV. Positive samples were found in 9 provinces of the country. Frequency of IgM antibodies against ZIKV was slightly higher in patients aged 5–9 years old, and in the north region of the country.

Keywords: antibodies zikv; igm antibodies; mozambique; virus; 2009 2015

Journal Title: BMC Research Notes
Year Published: 2019

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