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CRISPR/Cas9 from bench to bedside: what clinicians need to know before application?

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In October 2020, Dr. Emmanuelle Charpentier and Dr. Jennifer Doudna won the Nobel Prize in Chemistry for their pioneering work in precise genome editing using the CRISPR technology. Although CRISPR… Click to show full abstract

In October 2020, Dr. Emmanuelle Charpentier and Dr. Jennifer Doudna won the Nobel Prize in Chemistry for their pioneering work in precise genome editing using the CRISPR technology. Although CRISPR technology has developed rapidly in the last decade, there are still many uncertainties before eventual use in clinical settings. In this mini review, we summarize the current efforts in addressing the limitations of CRISPR technology and future directions.

Keywords: crispr; crispr technology; crispr cas9; bedside clinicians; cas9 bench; bench bedside

Journal Title: Military Medical Research
Year Published: 2020

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