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Mepivacaine-induced anaphylactic shock in a pregnant woman undergoing combined spinal and epidural anesthesia for cesarean delivery: a case report

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BackgroundAnaphylactic shock during pregnancy is a rare but life-threatening event for both the mother and the newborn.Case presentationA 42-year-old woman, who was pregnant with twins, was scheduled for cesarean delivery… Click to show full abstract

BackgroundAnaphylactic shock during pregnancy is a rare but life-threatening event for both the mother and the newborn.Case presentationA 42-year-old woman, who was pregnant with twins, was scheduled for cesarean delivery under combined spinal and epidural anesthesia. An epidural catheter was placed uneventfully. After spinal anesthesia, the patient exhibited skin symptoms and severe hypotension. The patient was diagnosed with anaphylaxis, and subsequently, treatment was started. Fetal heart rate monitoring revealed sustained bradycardia, and it was decided to proceed with cesarean delivery. After delivery, the mother’s vital signs recovered. Both infants were intubated due to birth asphyxia. Currently, the twins are 4 years old and exhibit no developmental problems. Clinical examination identified mepivacaine as the causative agent of anaphylaxis.ConclusionsThis case report highlights that upon occurrence of anaphylaxis during pregnancy, maternal treatment and fetal assessment should be started immediately. Indication for immediate cesarean delivery should be considered and a definite identification of the causative factor pursued.

Keywords: delivery; anesthesia; combined spinal; case; cesarean delivery; spinal epidural

Journal Title: JA Clinical Reports
Year Published: 2019

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