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α-Galactosylceramide: a potent immunomodulator produced by gut microbes1

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Intestinal bacteria have co-evolved with humans to respond to and regulate metabolism in a species-specific manner.  This commensalism, in turn, influences local and systemic energy homeostasis and immune regulation.  Although… Click to show full abstract

Intestinal bacteria have co-evolved with humans to respond to and regulate metabolism in a species-specific manner.  This commensalism, in turn, influences local and systemic energy homeostasis and immune regulation.  Although recent advances in high-throughput technologies have enabled researchers to connect these unique genetic and metabolic microbial signatures with human health and disease, gaps remain in our understanding of the specific mechanisms by which intestinal bacteria impact complex human biology.

Keywords: gut microbes1; biology; potent immunomodulator; galactosylceramide potent; immunomodulator produced; produced gut

Journal Title: Journal of Lipid Research
Year Published: 2019

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