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MONARCH 2: Abemaciclib in combination with fulvestrant in patients with HR+/HER2- advanced breast cancer who progressed on endocrine therapy

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1000Background: Abemaciclib, an oral, selective inhibitor of CDK4 & 6, dosed on a continuous schedule, demonstrated clinical activity as monotherapy in patients (pts) with treatment refractory horm... Click to show full abstract

1000Background: Abemaciclib, an oral, selective inhibitor of CDK4 & 6, dosed on a continuous schedule, demonstrated clinical activity as monotherapy in patients (pts) with treatment refractory horm...

Keywords: patients her2; combination fulvestrant; her2 advanced; fulvestrant patients; abemaciclib combination; monarch abemaciclib

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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