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Changes in p16INK4a (p16) expression, a biomarker of aging, in peripheral blood T-cells (PBTC) in patients receiving anthracycline (A) vs non-anthracycline (NoA) chemotherapy (CRx) for early-stage breast cancer (EBC).

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10060Background: Age-related accumulation of senescent cells plays a causal role in some aspects of mammalian aging. We have shown that the total-body burden of senescent cells can be estimated by… Click to show full abstract

10060Background: Age-related accumulation of senescent cells plays a causal role in some aspects of mammalian aging. We have shown that the total-body burden of senescent cells can be estimated by ...

Keywords: aging peripheral; p16ink4a p16; changes p16ink4a; expression biomarker; biomarker aging; p16 expression

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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