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Debio 1347, an oral FGFR inhibitor: Results from a first-in-human, phase I dose-escalation study in patients with FGFR genomically activated advanced solid tumors.

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2500Background: Oncogenic alterations in fibroblast growth factor receptors (FGFR) are seen across multiple solid tumor malignancies. Debio 1347 is an orally available, highly selective panFGFR inh... Click to show full abstract

2500Background: Oncogenic alterations in fibroblast growth factor receptors (FGFR) are seen across multiple solid tumor malignancies. Debio 1347 is an orally available, highly selective panFGFR inh...

Keywords: debio 1347; fgfr inhibitor; oral fgfr; 1347 oral; inhibitor results; results first

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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