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Gene expression analysis of tumor biopsies from a trial of durvalumab to identify subsets of NSCLC with shared immune pathways.

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3041Background: We previously reported that NSCLC pts with high pretreatment tumoral IFNG mRNA signature (sig) expression have improved outcomes (ORR, PFS, OS) to the anti-PD-L1 therapy durvalumab ... Click to show full abstract

3041Background: We previously reported that NSCLC pts with high pretreatment tumoral IFNG mRNA signature (sig) expression have improved outcomes (ORR, PFS, OS) to the anti-PD-L1 therapy durvalumab ...

Keywords: expression analysis; biopsies trial; gene expression; expression; tumor biopsies; analysis tumor

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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