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Clinical activity of the selective DRD2 antagonist ONC201, an imipridone, in metastatic endometrial cancer (mEC).

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5592Background: mEC is a generally incurable, with limited therapeutic options. ONC201 is the founding member of the new class of compounds called imipridones that are orally active small molecules... Click to show full abstract

5592Background: mEC is a generally incurable, with limited therapeutic options. ONC201 is the founding member of the new class of compounds called imipridones that are orally active small molecules...

Keywords: onc201 imipridone; clinical activity; antagonist onc201; selective drd2; drd2 antagonist; activity selective

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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