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IDO1 as a mechanism of adaptive immune resistance to anti-PD1 monotherapy in HNSCC.

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6053Background: Patients with recurrent/metastatic human papillomavirus-associated head and neck squamous cell carcinoma (HPV-HNSCC) demonstrate improved response rates to anti-PD-1 blockade, which... Click to show full abstract

6053Background: Patients with recurrent/metastatic human papillomavirus-associated head and neck squamous cell carcinoma (HPV-HNSCC) demonstrate improved response rates to anti-PD-1 blockade, which...

Keywords: adaptive immune; immune resistance; ido1 mechanism; resistance anti; hnscc; mechanism adaptive

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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