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Association of activating NOTCH1 mutations in adenoid cystic carcinoma with shorter progression-free survival to systemic therapy.

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6089Background: We previously reported that activating NOTCH1 mutations occurs in approximately 20% of ACCs and drive a phenotype with solid histology, liver and bone metastases, poor prognosis, an... Click to show full abstract

6089Background: We previously reported that activating NOTCH1 mutations occurs in approximately 20% of ACCs and drive a phenotype with solid histology, liver and bone metastases, poor prognosis, an...

Keywords: mutations adenoid; notch1 mutations; cystic carcinoma; association activating; activating notch1; adenoid cystic

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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