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EGFR/CD16A tetravalent bispecific antibody AFM24 to engage NK-cells to kill EGFR expressing tumor cells and safety results in cynomolgus monkey studies.

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e14001Background: The epidermal growth factor receptor is a target for the treatment of solid tumors, like CRC, HNSCC and NSCLC. Therapeutic success of EGFR-targeting agents depends on mutations de... Click to show full abstract

e14001Background: The epidermal growth factor receptor is a target for the treatment of solid tumors, like CRC, HNSCC and NSCLC. Therapeutic success of EGFR-targeting agents depends on mutations de...

Keywords: antibody afm24; cd16a tetravalent; egfr cd16a; afm24 engage; tetravalent bispecific; bispecific antibody

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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