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Novel porcupine (PORCN) inhibitor RXC004: Evaluation in models of RNF43 loss of function cancers.

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e14094Background: Wnt signalling initiates oncogenic pathways involved in tumour initiation, growth, differentiation and metastasis.1 Targeting the Wnt pathway is an attractive approach to cancer t... Click to show full abstract

e14094Background: Wnt signalling initiates oncogenic pathways involved in tumour initiation, growth, differentiation and metastasis.1 Targeting the Wnt pathway is an attractive approach to cancer t...

Keywords: evaluation models; rxc004 evaluation; novel porcupine; inhibitor rxc004; porcupine porcn; porcn inhibitor

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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