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IRX4204 in combination with erlotinib to target distinct pathways in lung cancer cells.

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e14095Background: IRX4204 is a Retinoid X Receptor (RXR) specific agonist (rexinoid). IRX4204 has high potency as a RXR agonist with low binding affinity to Retinoic Acid Receptors (RARs), PPAR, FX... Click to show full abstract

e14095Background: IRX4204 is a Retinoid X Receptor (RXR) specific agonist (rexinoid). IRX4204 has high potency as a RXR agonist with low binding affinity to Retinoic Acid Receptors (RARs), PPAR, FX...

Keywords: pathways lung; irx4204 combination; distinct pathways; target distinct; erlotinib target; combination erlotinib

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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