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Effect of Rho/ROCK pathway inhibition on metastasis-free and overall survival in biomarker selected, orthotopic, patient-derived models of pancreatic cancer.

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e15759Background: PC is a highly lethal disease which metastasises early. The sequencing efforts of the Australian Pancreatic Cancer Genome Initiative (APGI) identified ROCK-1 as a target of intere... Click to show full abstract

e15759Background: PC is a highly lethal disease which metastasises early. The sequencing efforts of the Australian Pancreatic Cancer Genome Initiative (APGI) identified ROCK-1 as a target of intere...

Keywords: rock pathway; pancreatic cancer; effect rho; cancer; rho rock

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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