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Factors influencing the use of thromboprophylaxis in cancer outpatients: CAT AXIS, a case-vignette study on clinical practice.

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e18276Background: Data on long-term venous thromboembolism (VTE) prophylaxis in cancer outpatients remain scarce. Our objective was to describe clinical practice and to identify factors influencing the use of thromboprophylaxis. Methods:… Click to show full abstract

e18276Background: Data on long-term venous thromboembolism (VTE) prophylaxis in cancer outpatients remain scarce. Our objective was to describe clinical practice and to identify factors influencing the use of thromboprophylaxis. Methods: CAT AXIS was a multicenter cross-sectional study based on the completion of physician-profile questionnaires and the assessment of 10 e-mailed credible clinical scenarios of lung, colon and breast cancer by each of participants using the case-vignettes validated method. Results: A total of 224 physicians participated allowing the completion and the analysis of 2,085 reviewed case vignettes corresponding to 765, 703 and 617 fictive clinical scenarios on lung, colon and breast cancers, respectively. The overall rate of thromboprophylaxis was 680/2085 (32.6%) among participants with a comparable proportion for the three types of cancer. Low-molecular-weight heparin (LMWH) was the most frequently used, by 92.7%, 93.8% and 83.9% of participants for lung, colon and breast cance...

Keywords: factors influencing; clinical practice; case; cancer outpatients; cancer; thromboprophylaxis

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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