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Population pharmacokinetic and pharmacodynamic analysis of osimertinib.

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e20536Background: Osimertinib is an oral, potent, irreversible, CNS active EGFR-TKI, selective for sensitizing (EGFRm) and T790M resistance mutations, indicated for the treatment of patients with T... Click to show full abstract

e20536Background: Osimertinib is an oral, potent, irreversible, CNS active EGFR-TKI, selective for sensitizing (EGFRm) and T790M resistance mutations, indicated for the treatment of patients with T...

Keywords: analysis osimertinib; pharmacodynamic analysis; population pharmacokinetic; pharmacokinetic pharmacodynamic; oncology

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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