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Detecting T790M mutation of tissue and plasma ctDNA samples by ARMS in EGFR-mutant NSCLC patients after disease progression.

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e20625Background: T790M mutation is the most common mechanism of acquired EGFR TKI resistance. The use of T790M-targeted EGFR TKIs needs re-biopsy to confirm the existence of sensitive mutation. Pe... Click to show full abstract

e20625Background: T790M mutation is the most common mechanism of acquired EGFR TKI resistance. The use of T790M-targeted EGFR TKIs needs re-biopsy to confirm the existence of sensitive mutation. Pe...

Keywords: tissue plasma; detecting t790m; plasma ctdna; t790m mutation; mutation tissue; mutation

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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