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Phase II trial of AZD1775 in combination with carboplatin and paclitaxel in stage IV squamous cell lung cancer (sqNSCLC): Preliminary results.

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e20672Background: WEE1, a dual serine/threonine and tyrosine kinase involved in regulation of the G2/M cell cycle checkpoint, is an essential component for proper DNA damage response. In combinatio... Click to show full abstract

e20672Background: WEE1, a dual serine/threonine and tyrosine kinase involved in regulation of the G2/M cell cycle checkpoint, is an essential component for proper DNA damage response. In combinatio...

Keywords: carboplatin paclitaxel; trial azd1775; cell; combination carboplatin; phase trial; azd1775 combination

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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