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Phase 1-2 study of TI-061 alone and in combination with other anti-cancer agents in patients with advanced malignancies.

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TPS3109Background: The cell surface protein CD47 is expressed or over-expressed on many tumor types. CD47 binds to signal regulatory protein alpha (SIRPα) on macrophages resulting in a “don’t eat m... Click to show full abstract

TPS3109Background: The cell surface protein CD47 is expressed or over-expressed on many tumor types. CD47 binds to signal regulatory protein alpha (SIRPα) on macrophages resulting in a “don’t eat m...

Keywords: alone combination; anti cancer; combination anti; phase study; 061 alone; study 061

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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