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INDUCE-1: A phase I open-label study of GSK3359609, an ICOS agonist antibody, administered alone and in combination with pembrolizumab in patients with advanced solid tumors.

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TPS3113Background: Inducible T cell Co-Stimulator (ICOS), a member of the CD28/B7/CTLA-4 receptor superfamily expressed on T cells after engagement with cognate antigen and activation, provides a c... Click to show full abstract

TPS3113Background: Inducible T cell Co-Stimulator (ICOS), a member of the CD28/B7/CTLA-4 receptor superfamily expressed on T cells after engagement with cognate antigen and activation, provides a c...

Keywords: gsk3359609 icos; study gsk3359609; phase open; induce phase; open label; label study

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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