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A phase II, open label study of tucatinib (ONT-380) combined with trastuzumab in patients with HER2+ metastatic colorectal cancer (mCRC)(MOUNTAINEER).

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TPS3624Background: To improve survival for patients with mCRC, efforts are needed to identify and treat actionable genomic alterations. HER2 is amplified in approximately 5-8% of patients with KRAS... Click to show full abstract

TPS3624Background: To improve survival for patients with mCRC, efforts are needed to identify and treat actionable genomic alterations. HER2 is amplified in approximately 5-8% of patients with KRAS...

Keywords: tucatinib ont; study tucatinib; phase open; ont 380; open label; label study

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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