LAUSR

415Background: The economic burden of MPC is substantial while treatment options are limited. This study aimed to compare healthcare costs and treatment patterns in MPC patients who initiated nab-P+G or FFX in a large insured US population. Methods: A retrospective study was conducted using the Truven Health MarketScan administrative claims databases. Adults who had ≥2 claims for pancreatic cancer, ≥1 claim with a secondary malignancy, completed ≥ 1 cycle of nab-P+G or FFX as 1L during 1/1/2013 and 3/31/2015, and had continuous enrollment in health plans for ≥6 months prior to and 3 months following the start of 1L were selected. Total healthcare costs and MPC-related treatment costs were measured per patient per month (PPPM) during 1L. Kaplan-Meier curve was used to describe time to treatment discontinuation (TTD) between groups. Results: 550 MPC patients met selection criteria (nab-P+G, n=294; FFX, n=256). Patients on nab-P+G were significantly older (mean age: 63.6 vs 58.8 years; p<0.001) and had highe...