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Inequality trends in proximal and distal colon cancers.

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565Background: Recently, the USPHTF released new colon cancer screening guidelines. No priority was given to any screening method. Given studies showing that Blacks had a greater proportion of proximal cancers,… Click to show full abstract

565Background: Recently, the USPHTF released new colon cancer screening guidelines. No priority was given to any screening method. Given studies showing that Blacks had a greater proportion of proximal cancers, we sought to better highlight the inequalities in outcomes in order to consider the appropriateness of sigmoidoscopies versus colonoscopies. Methods: The SEER database was utilized to pull incidence and 5 year relative survival data (1992-2013). Patients aged 50-84 were divided by race and percentage of a county’s population below the poverty line ( 15%). Adenocarcinomas were divided between distal cancer in the sigmoid, rectum, and anus versus cancer in the remainder of the colon. This data was analyzed using HDCalc, modelling rate difference, rate ratio, and the Index of Disparity. The Joinpoint regression program was then used to model Average Annual Percent Change (AAPC). Results: The AAPC in distal cancer incidence among Whites (-3.2%, [95% CI = -3.5%, -2.8%], p < 0.05) was greater than...

Keywords: trends proximal; colon; inequality trends; cancer; distal colon; proximal distal

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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