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Comprehensive molecular characterization of pediatric treatment-induced glioblastoma: Germline DNA repair defects as a potential etiology.

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10573Background: Pediatric treatment-induced high grade glioma (TIGs) are an incurable late complication of cranial radiation therapy or combined radiation/chemotherapy. We now evaluate copy-number... Click to show full abstract

10573Background: Pediatric treatment-induced high grade glioma (TIGs) are an incurable late complication of cranial radiation therapy or combined radiation/chemotherapy. We now evaluate copy-number...

Keywords: molecular characterization; comprehensive molecular; etiology; pediatric treatment; treatment induced

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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