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A phase II study of pazopanib with oral topotecan in patients with metastatic and non-resectable soft tissue and bone sarcomas.

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11550Background: Topotecan and pazopanib (PAZ) individually have clinical benefit in patients (pts) with sarcomas. PAZ is a multi-tyrosine kinase inhibitor and topotecan affects endothelial cells, ... Click to show full abstract

11550Background: Topotecan and pazopanib (PAZ) individually have clinical benefit in patients (pts) with sarcomas. PAZ is a multi-tyrosine kinase inhibitor and topotecan affects endothelial cells, ...

Keywords: pazopanib oral; patients metastatic; topotecan patients; oral topotecan; phase study; study pazopanib

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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