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Gene expression and cytokine modulation in a first in human (FIH) study of a pan BET inhibitor ABBV-075 in solid tumors.

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2570Background: ABBV-075 is an oral small molecule inhibitor of the BET family of bromodomain-containing proteins that function as regulators controlling many transcriptional programs required for ... Click to show full abstract

2570Background: ABBV-075 is an oral small molecule inhibitor of the BET family of bromodomain-containing proteins that function as regulators controlling many transcriptional programs required for ...

Keywords: expression cytokine; cytokine modulation; gene expression; abbv 075; modulation first; first human

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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