"ICONIC: Biologic and clinical activity of first in class ICOS agonist antibody JTX-2011 +/- nivolumab (nivo) in patients (pts) with advanced cancers."

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3000Background: ICOS is a costimulatory molecule expressed on the surface of activated T cells. JTX-2011 is an ICOS agonist designed to stimulate CD4 T effector (T eff) cells and deplete… Click to show full abstract

Keywords: clinical activity; icos agonist; biologic clinical; iconic biologic; jtx 2011

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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