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A phase 1/2A trial of synthetic DNA vaccine immunotherapy targeting HPV-16 and -18 after chemoradiation for cervical cancer.

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5525Background: DNA immunotherapies targeting HPV oncogenes, E6 and E7, have demonstrated clinical efficacy in pre-invasive cervical lesions. Here, we assessed the feasibility of chemoradiation and... Click to show full abstract

5525Background: DNA immunotherapies targeting HPV oncogenes, E6 and E7, have demonstrated clinical efficacy in pre-invasive cervical lesions. Here, we assessed the feasibility of chemoradiation and...

Keywords: dna; targeting hpv; trial synthetic; chemoradiation; synthetic dna; phase trial

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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