"Incidence of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) in patients (pts) with a germline (g) BRCA mutation (m) and platinum-sensitive relapsed ovarian cancer (PSR OC) receiving maintenance olaparib in SOLO2: Impact of prior lines of platinum therapy."

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Incidence of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) in patients (pts) with a germline (g) BRCA mutation (m) and platinum-sensitive relapsed ovarian cancer (PSR OC) receiving maintenance olaparib in SOLO2: Impact of prior lines of platinum therapy.

5548Background: Olaparib has been investigated and subsequently approved as maintenance treatment after response to platinum-based chemotherapy in pts with relapsed OC. A relationship between incre... Click to show full abstract

Keywords: syndrome mds; platinum; maintenance; myelodysplastic syndrome; olaparib; incidence myelodysplastic

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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