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Early clearance of plasma EGFR mutations as a predictor of response to osimertinib in the AURA3 trial.

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9027Background: In the Phase III AURA3 trial (NCT02151981), osimertinib, a third-generation EGFR-TKI, had significantly greater efficacy than platinum-pemetrexed in patients (pts) with advanced NSC... Click to show full abstract

9027Background: In the Phase III AURA3 trial (NCT02151981), osimertinib, a third-generation EGFR-TKI, had significantly greater efficacy than platinum-pemetrexed in patients (pts) with advanced NSC...

Keywords: trial; aura3 trial; egfr mutations; early clearance; clearance plasma; plasma egfr

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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