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Relationship between young age at diagnosis and disease free survival in premenopausal patients according to breast cancer subtypes.

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e12557Background: Previous studies have shown that young women are at high risk of recurrence and death. We aim to explore the roles of the clinic-pathological characteristics and treatment in disease… Click to show full abstract

e12557Background: Previous studies have shown that young women are at high risk of recurrence and death. We aim to explore the roles of the clinic-pathological characteristics and treatment in disease free survival for premenopausal breast cancer patients. Methods: We extracted information of operable premenopausal early breast cancer patients from January 2009 to December 2013 in the database of Comprehensive Breast Health Center in Ruijin Hospital, Shanghai, China. Chi-Square test, Kaplan-Meier analysis, and Multivariable Cox Proportional Hazards Models were adopted in the analysis. Results: A total of 1259 premenopausal women with stage I to III breast cancer were eligible for analysis. Among them 316 (25.1%) were 20% (57.6% vs 43.6%, p<0.001), ER negative tumors (34.8% vs 28.1, p=0.024), and triple negative and HER-2 positive breast cancer (21...

Keywords: breast; premenopausal; breast cancer; free survival; disease free

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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