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Plasma cell-free DNA copy number analysis by low coverage whole genome sequencing to monitor breast cancer relapse in CA15-3 and CEA silent patients.

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e13036Background: CA15-3 and CEA are the commonly used serum tumor biomarkers for monitoring breast cancer relapse. However, it is limited by sensitivity. Here we investigated copy number variation... Click to show full abstract

e13036Background: CA15-3 and CEA are the commonly used serum tumor biomarkers for monitoring breast cancer relapse. However, it is limited by sensitivity. Here we investigated copy number variation...

Keywords: ca15 cea; copy number; cancer relapse; breast cancer

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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