LAUSR

e13558Background: Breast intraductal papilloma comprises a wide spectrum of lesions, ranging from benign intraductal papilloma to papilloma with foci of atypia or papillary carcinoma, it can harbor occult malignancy also. The management of papilloma remains controversial. Methods: The current study is a retrospective analysis to investigate the intraductal breast papilloma and its coexisting lesions in the real-world practice. We identified 4450 intraductal breast papilloma patients with surgical excision from November 1999 through July 2017 at the First Affiliated Hospital of China Medical University. Results: 18.36% (817/4450) intraductal breast papilloma coexisting with malignant lesions of breast, 37.33% (1660/4450) coexisting with atypia hyperplasia, 25.24% (1123/4450) coexisting with benign lesions, only 19.10% (850/4450) without concomitant. 36.80% intraductal breast papilloma had nipple discharge, 51.46% had palpable breast mass. 16.45%had nipple discharge and palpable breast mass meanwhile. 28.18...