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AIDS-associated Kaposi sarcoma: A subset analysis of the County Hospital AIDS Malignancy Project (CHAMP study) exploring epidemiology, staging, and prognostic factors.

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e13587Background: Kaposi Sarcoma (KS) is a malignancy of endothelial cells. The epidemic form, AIDS-associated, has decreased from about 8 cases in the early 1990s to 0.9-2 cases/100,000 patient years (yrs)… Click to show full abstract

e13587Background: Kaposi Sarcoma (KS) is a malignancy of endothelial cells. The epidemic form, AIDS-associated, has decreased from about 8 cases in the early 1990s to 0.9-2 cases/100,000 patient years (yrs) in the United States (US) between 2000-2013. Most epidemiological studies examine large geographic areas, and insights into cancer/HIV in the underserved populations have been underrepresented in the literature. Stroger Hospital (CCH) and the Ruth M. Rothstein CORE Center (CC) are the largest health providers for HIV+ patients (pts) in Chicago. CCH/CC treat about 5,000 HIV+ individuals per year and 40 newly diagnosed HIV-associated cancers yearly. The CHAMP Study is a prospective data base of pts diagnosed with HIV/AIDS-associated malignancies. Here we present an analysis of the KS cohort. Methods: Patient, HIV/cancer characteristics, and survival data were compiled from the KS cohort. Survival data was analyzed using Kaplan-Meier analysis and Cox Proportional Hazards model and statistical comparisons ...

Keywords: kaposi sarcoma; champ study; analysis; aids associated; malignancy; epidemiology

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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