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First-in-human phase I trial of anti-hepatocyte growth factor (HGF) antibody (YYB101) in refractory solid tumor patients.

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e14501Background: The aim of this study was to determine the maximum tolerate dose (MTD), safety, pharmacokinetics (PK), and pharmacodynamics (PD) of YYB101, a hepatocyte growth factor (HGF) neutra... Click to show full abstract

e14501Background: The aim of this study was to determine the maximum tolerate dose (MTD), safety, pharmacokinetics (PK), and pharmacodynamics (PD) of YYB101, a hepatocyte growth factor (HGF) neutra...

Keywords: growth factor; factor hgf; hepatocyte growth

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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