"Novel formulation of abiraterone acetate with significantly higher bioavailability and eliminated food effect might allow higher abiraterone exposure and better patient outcome."

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Novel formulation of abiraterone acetate with significantly higher bioavailability and eliminated food effect might allow higher abiraterone exposure and better patient outcome.

e17036Background: Zytiga (Abiraterone acetate, AA) is known to exhibit very low bioavailability and a significant positive food effect. This is attributed to the inadequate and variable dissolution... Click to show full abstract

Keywords: food effect; abiraterone; abiraterone acetate; bioavailability

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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