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Co-isolation and analysis of extracellular vesicle (EV)-associated DNA and cell free DNA (cfDNA) to improve the diagnostic and prognostic value of circulating BRAF V600E in metastatic melanoma patients.

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e21564Background: Detection of BRAF V600E on cell free tumor DNA (cfDNA) is emerging as a promising means to improve patient’s stratification or enable BRAFi therapy monitoring in a minimally invas... Click to show full abstract

e21564Background: Detection of BRAF V600E on cell free tumor DNA (cfDNA) is emerging as a promising means to improve patient’s stratification or enable BRAFi therapy monitoring in a minimally invas...

Keywords: braf v600e; dna cfdna; cell free; dna

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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