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Cell-free circulating tumor DNA (cfDNA) to identify germline (GL) and somatic BRCA alterations (alts) in men with advanced prostate cancer (ProsCA).

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e24287Background: cfDNA NGS is a non-invasive tumor profiling method which interrogates circulating tumor and leukocytic DNA, and thus has the potential to identify GL alts. These “secondary findin... Click to show full abstract

e24287Background: cfDNA NGS is a non-invasive tumor profiling method which interrogates circulating tumor and leukocytic DNA, and thus has the potential to identify GL alts. These “secondary findin...

Keywords: dna; cell free; cfdna; circulating tumor; free circulating; tumor

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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