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A phase 2 study of poziotinib in patients with EGFR or HER2 exon 20 mutation-positive non-small cell lung cancer.

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TPS9106Background: Poziotinib is a novel, oral, quinazoline-based pan-HER inhibitor that irreversibly blocks signaling through the EGFR family of tyrosine-kinase receptors, including human epiderma... Click to show full abstract

TPS9106Background: Poziotinib is a novel, oral, quinazoline-based pan-HER inhibitor that irreversibly blocks signaling through the EGFR family of tyrosine-kinase receptors, including human epiderma...

Keywords: poziotinib patients; poziotinib; egfr her2; phase study; patients egfr; study poziotinib

Journal Title: Journal of Clinical Oncology
Year Published: 2018

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