LAUSR

353Background: The study aimed to develop a nomogram to predict overall survival (OS) among hepatocellular carcinoma (HCC) patients with BCLC stage C after stereotactic body radiotherapy (SBRT). Methods: Clinical data from the multicenter study consisted of 270 HCC patients with BCLC stage C. The patients underwent SBRT with a median dose of 40 Gy (range: 25-60 Gy) in 2-6 fractions. The model included age, gender, ECOG performance status, etiology (HBV, HCV, and non-B, non-C), number of tumor, tumor size, AFP level, presence of macrovascular invasion, Child-Pugh class, N stage, M stage, sorafinib use, and biologically effective dose. Cox’s proportional hazards models were utilized to estimate regression coefficients of death risk predictors and derive risk scores. The area under receiver operating curve (AUROC) was used to evaluate the performance of the risk models. Results: The median survival was 12.6 months, with 1-year and 2-year OS rates of 51.6% and 30.8%, respectively. Multiple regression showed a...